Is It The Right Treatment Option For You?

What Is Ketamine?

Ketamine is an FDA-approved medication that has been in wide use around the world. It was approved by the FDA in 1970. It is considered a very safe and effective treatment, both in surgical settings and as an alternate treatment for multiple health conditions including chronic refractory depression, other mental health conditions, various chronic pain syndromes, and post-traumatic stress syndrome. Many people who have lived their entire lives struggling with these conditions are finding relief from treatment with ketamine. Though not originally approved for these conditions by the FDA, this is safe OFF-LABEL use of this medication, administered in a controlled setting.

Each person may experience a slightly different sensation during the infusion and this may include slight ”dissociation,” which is when there is a sense of disconnect between mind and body. Most patients describe it as a relaxing or positive feeling and it can be transformative and ”life-altering.”

The Ketamine Clinic of Seattle is committed to helping people in a comfortable and supportive clinical environment. Our treatment protocols are research-based, with the needs of each individual considered. We are committed to providing you with the best possible experience and your safety and well-being are of utmost importance.

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Ketamine For Depression

Up to 17 million people in the United States suffer from depression and at least one third of these are resistant to standard treatments.

Current research studies have shown ketamine to provide rapid relief to many of those individuals.

Ketamine seems to work through several pathways. One likely target for ketamine is N-methyl-D-asparate (NMDA) receptors in the brain. It binds to the receptors and blocks them which then increases a neurotransmitter called glutamate in the spaces between neurons. This activates connections in another receptor, called the AMPA receptor. It is through these mechanisms that new pathways are used or formed. This is known as synaptogenesis and this process likely affects mood, thought patterns, and cognition.

Ketamine may also help to reduce inflammation and also works on other receptor sites in the body. Research continues on this novel medication. Research has shown that ketamine “re-balances” certain neurotransmitters in patients who suffer with depression, obsessive thoughts, anxiety, and suicidal thinking. Ketamine may also cause re-vascularization of neurons that have atrophied in the brain. And this may be how ketamine treats depression so effectively compared to standard antidepressants.

We encourage all patients to take an integrative and active approach to care and implement lifestyle changes, nutritional supplementation, dietary modifications, counseling, and/or continued oral prescription medications to enhance their treatment plan and long-term health goals.

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